Hesperidin is a citrus bioflavonoid and enhances the activity of vitamin C. It is an antioxidant. It strengthens capillaries, veins and arteries and is highly beneficial for diabetics, where the arterial system in breaking down. Anyone with poor circulation in the legs or with varicose veins, or hemorrhoids will benefit from this supplement. Rutin is another bioflavonoid from citrus. You can also make your own bioflavonoids from this recipe.